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TRIALS.AI BY ZS

AI-Powered Clinical Study Design
For the Modern Research Team

Advanced agentic AI technology digitizes, automates, and adds intelligence to every aspect of trial creation.

We see a world where optimized studies feed upstream and downstream artifacts and systems resulting in increased efficiency, shorter timelines and better outcomes – because patients don't have time to wait!

Applications & Data Products for Modern Research

02 - Application

Library Manager

Reusable knowledge and language in a contextually relevant manner. Access your organization's collective wisdom instantly.

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03 - Data Product

Clinical Studies Ontology

500K+ BFO-compliant classes. A shared semantic framework connecting clinical study concepts across documents and systems.

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Meet Franklin - your AI Optimization Advisor

Expert guidance across clinical science, biostatistics, regulatory strategy, and medical writing... helping you optimize study design in real time.

Decisions Before Documents

Most tools focus on writing protocols. Franklin focuses on improving the design decisions that shape the protocol.

Explore alternatives across endpoints, eligibility criteria, schedules of activities, patient populations, and operational complexity - before they become locked into downstream documents.

Intelligence Grounded in Structured Study Data

Franklin is powered by structured study data connected through the Trials.ai ontology and Dynamic Data Graph.

This enables Franklin to reason across historical clinical trials, operational outcomes, and protocol design patterns to surface meaningful design insights. Not just text generation.

Cross-Functional Expertise Built Into the System

Study design requires expertise across clinical science, biostatistics, regulatory strategy, protocol development, and clinical operations.

Franklin brings those perspectives into a single intelligence layer to help teams evaluate tradeoffs across scientific, statistical, and operational dimensions.

Software products that combine data-driven intelligence with next-gen technology are embedded in our DNA

ZS is committed to transforming clinical development through technology, data science, and deep domain expertise - partnering with the world's leading life sciences companies to bring therapies to patients faster.

900+
Dedicated product team members
100+
Life science companies served
40+ years
Life sciences expertise
◆ Patented

US Patent No. 11,328,795 — Intelligent Planning, Execution, and Reporting of Clinical Trials, including the Patient Burden Index. Inventors: Kim Walpole, Thomas Walpole et al. Assigned to ZS Associates Inc.

Rosalind Franklin

Rosalind Franklin

Chemist & X-ray crystallographer, 1920 - 1958

Franklin is named in honor of Rosalind Franklin, whose pioneering work using X-ray diffraction helped reveal the structure of DNA and transform modern science.

Inspired by her commitment to scientific rigor and discovery, Franklin brings evidence-driven insight to clinical study design... helping teams navigate complex decisions with clarity and confidence.